Sildenafil - mataki, alamomi, contraindications, sakamako masu illa

Sildenafil magani ne da ake amfani da shi don magance tabarbarewa. An fara rubuta shi ga marasa lafiya da hauhawar jini na huhu, amma an lura da tasirin sa akan jima'i da sauri. Yanzu magani ne akai-akai shawarar ga mazan da ke fama da matsalar rashin ƙarfi. Abin da kuke buƙatar sani game da Sildenafil?

1. Menene Sildenafil?

Babban magunguna don magance tabarbarewar erectile sune masu hana masu hana nau'in phosphodiesterase 5 (PDE-XNUMX). Mafi shahararren magani irin wannan shine Viagra.

An fara gabatar da shi a cikin 1998 zuwa kasuwannin Amurka kuma tun daga lokacin yana samuwa kusan ko'ina a duniya. Duk da haka, ya kamata a tuna cewa akwai wasu magunguna da yawa tare da tsarin aiki iri ɗaya. Mafi shahara:

• Sildenafil
• tadalafil,
• Vardenafil.

Gabatarwar Sildenafil da dukkan nau'ikan kwayoyi daga wannan rukunin sun kasance bazuwar. Da farko, an wajabta sildenafil ga marasa lafiya tare da hauhawar jini na huhu. Nasa tasirin haɓaka haɓakawa marasa lafiya sun lura da sauri, wanda ya haifar da canji a cikin alamun amfani da wannan magani.

Kafin zamanin sildenafil, maza sun yi amfani da su kuma sukan yi amfani da wasu da yawa, abin da ake kira mashahuri, takamaiman. Yana da kyau a ce a cikin kowace al'ada akwai wani abu da ya kamata ya inganta ƙarfi. Kuma a, mutane sun kasance suna amfani da magunguna masu zuwa don tabarbarewar erectile shekaru aru-aru:

• Foda kahon karkanda ya shahara sosai a kasar Sin,
• a wasu al’adu kuwa jinin jemage ne, da ƙwayoyin fox da na barewa, da kwakwalwar kyanwa,
• wormwood, verbena, ginger, tafarnuwa, lovage, nutmeg, cloves.

Ya kamata a jaddada cewa yawancin waɗannan abubuwa ba su da ingantaccen tsarin aiki. Tasirinsu ya dogara ne akan bangaskiyar sihiri kawai a cikin aikinsu.

2. Yadda Sildenafil ke aiki

Sildenafil an fara haƙƙin mallaka a cikin 1996 kuma ya shiga kasuwa bayan shekaru biyu. A halin yanzu, magani ne don ƙarfi, tare da hauhawar jini na farko (III aikin aji) da kuma wasu cututtuka na nama mai haɗawa.

Magunguna sun ƙunshi milligrams 25-100 na sildenafil citrate. Sildenafil yana ƙunshe a cikin tsarinsa na piperazine motif da analog na guanine, 1H-pyrazolo [4,3-d] pyrimidine. Tsarin phenol na tsakiya yana daidai da ribose, kuma ragowar sulfone yayi daidai da rukunin phosphate na nucleotide.

Wannan fili a cikin jiki yana hana galibi nau'in phosphodiesterase 5 (PDE5) - kusanci ga sauran nau'ikan wannan enzyme ya ragu sosai. PDE5 ya raba cGMP, wanda ke da alhakin shakatawa tsokoki masu santsi da kuma ƙara yawan jini zuwa ga jikin kogo.

Yayin motsa jiki, ƙwayoyin jijiya sun fara samar da nitric oxide (NO), wanda ya sa ya yiwu a yi amfani da cGMP. An katange ta sildenafil, PDE5 yana ba ku damar "ci gaba da" tsauri.

Duk da haka, a cikin maza da yawa, saboda neurosis, damuwa na tunani, rashin daidaituwa na hormonal, ko rashin lafiya na tsarin juyayi mai tausayi, samar da nitric oxide ta sel jijiya yana da rauni sosai, wanda ke haifar da rauni da gajere. Mafi saurin sha yana faruwa bayan shan miyagun ƙwayoyi akan komai a ciki. Ana fitar da shi ne da najasa (kimanin kashi 80 cikin dari) kuma a ɗan ƙarami da fitsari.

3. Alamu don amfani da Sildenafil

Goma magani don iko yana ba wa maza damar samun tsaiko na dindindin da yin jima'i. Amfanin wannan magani shine gaskiyar cewa tashin hankali baya faruwa nan da nan bayan shan kwaya, amma ana buƙatar motsa jiki (ba kamar magungunan prostaglandin ba).

Ana ba da shawarar shan miyagun ƙwayoyi sa'o'i ɗaya zuwa shida kafin jima'i da aka tsara. Bayan da likita yayi la'akari da digiri da yanayin rashin ƙarfi, likita ya zaɓi kashi na miyagun ƙwayoyi (25, 50 ko 100 MG), wanda zai ba ku damar kula da haɓaka daga minti 30 zuwa awa daya. Ana ba da shawarar shan miyagun ƙwayoyi sau ɗaya a rana. Ga mutanen da ke da matsanancin gazawar koda, ana ba da shawarar rage kashi.

4. Contraindications

Bai kamata maza su sha wannan maganin a ƙarƙashin waɗannan sharuɗɗa ba:

• cututtuka na jijiyoyin jini,
• m hauhawar jini,
• gazawar jini (NYHA class III da IV),
• tare da bugun zuciya na baya-bayan nan (makonni biyu na farko),
• obstructive cardiomyopathy
• tare da arrhythmias na ventricular (m, lalacewa ta hanyar motsa jiki, damuwa, motsin zuciyarmu),
• tare da mummunar cutar valvular
• mai tsanani hanta da koda gazawar,
• bayan bugun jini
• tare da canje-canje masu lalacewa a cikin retina (misali, retinitis pigmentosa),
• hypotension,
• tare da hypersensitivity zuwa sassan da miyagun ƙwayoyi.

Siledenafil Yana da tasirin vasodilator kuma yana iya zama haɗari ga mutanen da ke shan magungunan zuciya da jijiyoyin jini. Cikakken hani ga shan miyagun ƙwayoyi shine shan Nitrate da Molsidomine.

Ya kamata kuma a yi la'akari da bambance-bambance a cikin metabolism na wannan magani. An rushe shi a cikin hanta, wanda ke nufin cewa zubar da wannan magani yana raguwa a cikin mutanen da suka lalace hanta da kuma fiye da shekaru 65, kuma yawan allurai na iya zama haɗari. Magunguna da aka sani don hulɗa tare da siledenafil sun haɗa da:

• assimilate,
• erythromycin,
• ketoconazole,
• Rifampicin da sauran su.

Sildenafil, saboda tsarin vasodilating, yana rage karfin jini. Har zuwa yau, mutuwar saboda amfani da sildenafil ya faru a cikin mutanen da ke shan magungunan zuciya, kamar, alal misali, nitrates ko wasu. magunguna don rage hawan jini.

Ba a ba da shawarar wannan magani don rashin ƙarfi a cikin maza a ƙarƙashin shekaru 18 da lahani na azzakari (kamar flexure, cavernous fibrosis ko cutar Peyronie) bayan prosthesis na azzakari kuma tare da yanayin da ke haifar da su zuwa priapism (misali, sickle cell anemia, mahara myeloma, ko cutar sankarar bargo). Ba a yi amfani da miyagun ƙwayoyi a matsayin wani ɓangare na maganin haɗin gwiwa don maganin tabarbarewar erectile.

5. Sakamakon sakamako bayan shan sildenafil

Sildenafil magani ne da yawancin maza ke jurewa. Yana faruwa ko da yake illa na sildenafil, Waɗannan sun haɗa da:

• ciwon kai da dizziness
• jajayen fuska
• dyspepsia (cututtukan ciki),
• hangen nesa).

Ƙananan sakamako masu illa na shan siledenafil sune:

• kumburin mucosa na hanci,
• ciwon mafitsara da urethra,
• tsoka da ciwon haɗin gwiwa.

Abubuwan da ke sama na sildenafil an ruwaito su da kusan 35 bisa dari. marasa lafiya. Bayyanar waɗannan alamun yana da alaƙa da toshe nau'in PDE 5, da kuma wasu nau'ikan a cikin wasu gabobin. Mutanen da ke fama da bugun zuciya mara kyau, hawan jini, da kuma yanayin bugun zuciya na iya fuskantar matsaloli masu tsanani, gami da ciwon zuciya da mutuwa (saboda sakin nitric oxide).

Yin amfani da miyagun ƙwayoyi ta hanyar maza masu lafiya na iya haifar da ƙarin matsaloli wajen samun tsaiko (ba tare da shan magani ba), kumburin azzakari mai raɗaɗi, kumburi da lalata jikin kogo.

Yawan amfani da shi na iya ci gaba da tashi har zuwa awanni 6. Saboda yiwuwar nakasar gani da juwa bayan shan miyagun ƙwayoyi, ya kamata ku guje wa tuƙin motoci da aiki tare da hanyoyin.

6. Abubuwan da ke haifar da rashin ƙarfi

Rashin ƙarfi (ED) an bayyana shi azaman "lalacewar jima'i wanda ke bayyana rashin karfin jiki ko kuma fitar da maniyyi duk da jin dadi da gamsarwa a gaban gaba”. Rashin ƙarfi ba shine rashin tsaurin kai ba yayin jima'i na yau da kullun, wanda yawanci yana tare da damuwa.

Za mu iya magana game da rashin lafiya lokacin matsalolin mazauni kuma fitar maniyyi yakan bayyana sau da yawa, duk da alakar da ke tsakanin ma’aurata. Ana iya raba wannan cuta zuwa firamare da sakandare (yana faruwa bayan lokacin jima'i na yau da kullun).

Tushen matsaloli a cikin cikakkiyar rayuwar jima'i na iya zama tunani (rashin hankali) da abubuwan halitta (somatic).

Rukuni na farko ya hada da: tsoron saduwa, Tsoron ciki maras so, hadaddun, laifi, zunubi, damuwa, rikice-rikice na ci gaban jima'i, rikice-rikice (hanyoyin mayar da hankali kan kai). Yawancin lokaci a irin waɗannan yanayi, lokacin barci ko al'aura, halayen al'ada ne.

Abubuwan da ke haifar da rashin ƙarfi na jiki sun haɗa da cututtuka (ciwon sukari mellitus, sclerosis mai yawa, tetraplegia, ALS, lahani na zuciya, hauhawar jini mai tsanani, phimosis, flushing, cutar Peyronie) ko canje-canje masu alaƙa da shekaru (andropause) waɗanda ke hana erections. Wasu abubuwan kara kuzari ( barasa, amphetamines) da kwayoyi (SSRIs, SNRIs) na iya haifar da rashin ƙarfi.

Ji daɗin sabis na likita ba tare da layi ba. Yi alƙawari tare da ƙwararren mai takardar sayan magani da e-certificate ko jarrabawa a abcHealth Nemo likita.